ENOLA (Interprofessional Education and Collaboration to Broaden Sexual Education) was held to improve our knowledge about comprehensive sexuality education by applying Interprofessional Education (IPE) and Interprofessional Collaboration (IPC) among medical students. From 41 college students, 97.6% of respondents agreed that comprehensive sexual education is necessary. 92.7% agreed that sexual education should be delivered as early as possible by paying attention to age development and with the correct method. 92,7% said it would be easier to convey comprehensive sexual education by using IPE and IPC methods. These data show that college students were interested in the collaboration from various majors to broaden sexual education. The goal of this project is to increase the knowledge of participants from the Faculty of Medicine Sebelas Maret University, members of SCORA & SCOME CIMSA FK UNS regarding sexual education and increasing the promotion of sexual education based on health collaboration. ENOLA has two series of events. On August 21st, 2021, we held training about Comprehensive Sexual Education delivered by Alvin from Tabu.id and a talkshow about interprofessional education and collaboration with Ncan, Deni, and Brian from Alura. On August 28th, 2021, we held a battle of wits. Battle of wits consists of three stages. The first stage is the multiple-choice stage. The semifinal round is a quiz with 3 forms of sessions of the battle of wits with 15 problems given in each session. The final round is a case study of Comprehensive Sexual Education, interprofessional education, and collaboration judged by Kevlar Azri Ghurafa as former HRDC SCOME CIMSA Indonesia, and Diesta Maylitadara as former PETRA SCORA CIMSA FK UNS 2017/2018. Nurul Ismatun Khasanah, Peti Apriliani, and Muhammad Zuhdi Rahman came out as the winner of this competition . After the event finished, most of the participants gave good scores to the series of ENOLA’S events. They gave a 9/10 score and said that all of the series of ENOLA’S events were impactful, educated, and motivated participants to think critically about Comprehensive Sexual Education, interprofessional education, and collaboration. This statement is proven by an increase in the knowledge of the participants by 20,67% for CSE topics and 18% for IPE and IPC topics. This event was very impactful and found interesting amongst the participants.